publications

Hu SB, and Li JB. RNA editing and immune control: from mechanism to therapy. Curr Opin Genet Dev 2024, 86: 102195.

https://www.sciencedirect.com/science/article/pii/S0959437X24000443

Hu SB*, Heraud-Farlow J*, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR, Li JB. ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation. Mol Cell2023, 83: 3869-3884.

https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00740-2

• Previews by Dorrity TJ and Chung H, Mol Cell, 2023, 83(21): 3760-3762

Wang Y*, Hu SB*(co-first author), Wang MR, Yao RW, Wu D, Yang L, Chen LL. Genome-wide screening of NEAT1 regulators reveals cross-regulation between paraspeckles and mitochondria. Nat Cell Biol2018, 20:1145–1158.

https://www.nature.com/articles/s41556-018-0204-2

• News and Views by Fox AH, Nat Cell Biol, 2018, 20(10): 1108-1109

Hu SB, Yao RW, Chen LL. Shedding light on paraspeckle structure by super-resolution microscopy. J Cell Biol 2016, 214(7):789-91.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037413

Hu SB, Xiang JF, Li X, Xu YF, Xue W, Huang M, Wong CC, Sagum CA, Bedford MT, Yang L, Cheng D and Chen LL. Protein arginine methyltransferase CARM1 attenuates the nuclear retention of mRNAs containing IRAlus at paraspeckles. Genes & Dev 2015, 29: 630-645. https://genesdev.cshlp.org/content/29/6/630.long

• Perspectives by Elbarbary RA and Maquat LE, Genes & Dev, 2015, 29:687-689

• Research highlights by Bull Chin Acad Sci, 2015, 29:108

Yin QF*, Hu SB*(co-first author), Xu YF, Yang L, Carmichael GG, Chen LL. SnoVectors for nuclear expression of RNA. Nucleic Acids Res 2015, 43:e5.

https://academic.oup.com/nar/article/43/1/e5/2902592

Heraud-Farlow JE, Taylor SR, Chalk AM, Escudero A, Hu SB, Goradia A, Sun T, Li Q, Nikolic I, Li JB, Fidalgo M, Guallar D, Simpson KJ, Walkley CR. GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing. Sci Immunol. 2024;9(101):eadk0412.

https://www.science.org/doi/full/10.1126/sciimmunol.adk0412

Sun T, Qin L, Geisinger J, Hu SB, Fan B, Su SC, Tsui WT, Guo HC, Ma JB, Li JB. A small subset of cytosolic dsRNAs must be edited by ADAR1 to evade MDA5-mediated autoimmunity. bioRxiv 2022.

https://www.biorxiv.org/content/10.1101/2022.08.29.505707v1.full

Xing YH, Bai Z, Liu CX, Hu SB, Ruan M, Chen LL. Research progress of long noncoding RNA in China. IUBMB Life 2016.

https://iubmb.onlinelibrary.wiley.com/doi/abs/10.1002/iub.1564